Charcot-Marie-Tooth (CMT) is an inherited disease that results in the gradual loss of function and sensation in the hands, arms, legs and feet. Over 100 different gene mutations have been identified that cause CMT. The pedigree diagram shows the inheritance of one form of CMT in part of a family. The allele for CMT can be represented by the letter c in this recessive pattern of inheritance. Which allele combinations could individual 3 have? (1)

A.
CC only
B.
cc only
C.
CC or cc
D.
CC or Cc
Biology
IGCSE&ALevel
EDEXCEL
Exam No:WBI1101-que-20241008 Year:2024 Question No:(a)(ii)

Answer:

D

Knowledge points:

CH2 – Membranes, Proteins, DNA and Gene Expression

Solution:

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