Mammals produce ATP by anaerobic and aerobic respiration. The photograph shows a coyote. (Source: © Shaun Cunningham/Alamy Stock Photo) Some coyotes have been poisoned with cyanide to prevent them from killing the livestock of farmers. Cyanide inhibits cytochrome oxidase, the last carrier in the electron transport chain (ETC). Explain how the action of cyanide would kill a coyote. (4) ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................

Biology
IGCSE&ALevel
EDEXCEL
Exam No:wbi15-01-que-20240608 Year:2024 Question No:6(b)

Answer:

An answer that includes four of the following points:
- \{cytochrome oxidase cannot be oxidised /electrons are not passed along electron transfer chain / reduced \{NAD / FAD / coenzyme\} are not oxidised\} (1)
- cells \{respire anaerobically / only do glycolysis\} (1)
- \{insufficient / less / no\} \{ATP / energy\} for \{contraction of muscles / contraction of heart / metabolic reactions\} (1)
- pyruvate converted to \{lactate / lactic acid\} (1)
- (accumulation of) \{lactate / lactic acid\} results in a decreased pH (1)
- resulting in denaturing of enzymes / change in \{secondary / tertiary\} structure (of proteins) (1)

Knowledge points:

CH7 – Respiration, Muscles and the Internal Environment

Solution:

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