Mutations in the MYO6 and POU4F3 genes have been associated with a form of hereditary hearing loss in humans. Researchers studying the genes have proposed that POU4F3 encodes a transcription factor that influences the regulation of MYO6. Which of the following questions will best help guide the researchers toward a direct test of their proposal?

A.
Have mutations in other genes also been associated with hearing loss?
B.
In what types of cells are the mutant forms of the POU4F3 gene expressed?
C.
Are mutations in the MYO6 and POU4F3 genes also found in mice?
D.
Do mutations in the POU4F3 gene affect MYO6 mRNA levels in cells?
Biology
AP
College Board
Exam No:Sample Exam Questions Year:2024 Question No:3

Answer:

D

Knowledge points:

6.5 Regulation of Gene Expression

Solution:

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