Some diseases, and certain cancers, are thought to be caused by a lack of specific neurotransmitters. This means they can be treated using drugs which increase the concentration of these neurotransmitters. Some of these drugs are manufactured using genetically modified (GM) organisms. Bevacizumab (BVZ) is an antibody used to treat brain cancer patients. This antibody is produced using animal cell cultures. A new method of producing BVZ has been developed using genetically modified (GM) rice. The graph compares the antigen binding activity of a BVZ antibody produced using: - a control using non-transformed rice - animal cell culture - four strains of GM rice (A, B, C and D). Describe three conclusions that can be made from these results. (3) ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................ .................................................................................................................................................................................................................................................................................

Biology

IGCSE&ALevel

EDEXCEL

Exam No：WBI1501-que-20241024 Year：2024 Question No：7(b)(i)

Answer:

An answer that includes three of the following points:
- all \{have antigen binding activity / produce BVZ\} (1)
- \{animal culture and GM rice / all other / GM rice\} have higher (antigen) binding activity than non-transformed rice (1)
- animal culture has highest (antigen) binding activity (than all others) (1)
- strain B has highest (antigen) binding activity of the GM rice / strain D has lowest (antigen) binding activity of the GM rice (1)

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