Some diseases, and certain cancers, are thought to be caused by a lack of specific neurotransmitters. This means they can be treated using drugs which increase the concentration of these neurotransmitters. Some of these drugs are manufactured using genetically modified (GM) organisms. Bevacizumab (BVZ) is an antibody used to treat brain cancer patients. This antibody is produced using animal cell cultures. A new method of producing BVZ has been developed using genetically modified (GM) rice. The graph compares the antigen binding activity of a BVZ antibody produced using: - a control using non-transformed rice - animal cell culture - four strains of GM rice (A, B, C and D). Explain how BVZ antibodies can cause the destruction of cancer cells. (2) ................................................................................................................................................................................................................................................................................ ................................................................................................................................................................................................................................................................................
Exam No:WBI1501-que-20241024 Year:2024 Question No:7(b)(ii)
Answer:
A description that includes two of the following points:
- (BVZ antibodies are) complementary to \{antigens / receptors / (specific) membrane protein\} on cancer cel (1)
- (BVZ / antibody) binds to \{antigens / receptors / (specific) membrane protein\} (of cancer cells) (1)
- resulting in \{(enhanced) phagocytosis / engulfing by phagocytes / destruction by phagocytes\} (1)
- (BVZ antibodies are) complementary to \{antigens / receptors / (specific) membrane protein\} on cancer cel (1)
- (BVZ / antibody) binds to \{antigens / receptors / (specific) membrane protein\} (of cancer cells) (1)
- resulting in \{(enhanced) phagocytosis / engulfing by phagocytes / destruction by phagocytes\} (1)
Knowledge points:
CH8 – Coordination, Response and Gene Technology
Solution:
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